Rheumatoid arthritis is a chronic disease that leads to inflammation of the joints and surrounding tissues. It can also affect other organs. Vectra® DA is an advanced blood test that helps patients and their doctors to better assess RA disease activity.
Nearly 1.5 million Americans are living with rheumatoid arthritis (RA), a chronic disease that affects women two to three times more often than men. RA is an autoimmune disease that mainly affects the joints – especially in the hands and feet – but can also have an impact on many other parts of the body, including the heart, lungs and blood vessels. RA causes pain, swelling and redness in the affected joints and, over time, cartilage and bone can wear away, causing increasing pain and eventually leading to disability.
Patients and Physicians Work Together to Manage RA
Stephanie talks about how she has taken control of her life by tracking her disease and partnering with her rheumatologist.
Managing Rheumatoid Arthritis
Regular, objective assessments of RA disease activity are key to achieving target levels of disease activity and improving patient outcomes.1-7 Management of RA is largely informed by assessments of clinical symptoms, joint evaluations and laboratory testing for C-reactive protein (CRP) and/or erythrocyte sedimentation rate (ESR). However, these measures cannot always identify underlying disease activity or assess the risk of future structural damage, which may continue even when signs and symptoms appear to be controlled.8-10
Using Blood Tests to Monitor RA Disease Activity
RA is a disease that involves complex interactions among multiple proteins in a number of tissues, including bone, cartilage and synovium.11 Vectra® DA is a multi-biomarker blood test that simultaneously measures 12 key biomarkers consistently associated with RA disease activity and combines them in a single score between 1 and 100. By providing an objective and reproducible measure of RA disease activity that can be used to complement existing assessment tools, Vectra DA provides an objective and reproducible measure of RA disease activity that can be used to complement existing assessment tools.12,13
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2. Rantalaiho V, et al, for the FIN-RACo Trial Group. Early combination disease-modifying antirheumatic drug therapy and tight disease control improve long-term radiologic outcome in patients with early rheumatoid arthritis: the 11-year results of the Finnish Rheumatoid Arthritis Combination Therapy trial. Arthritis Res Ther. 2010;12(3):R122.
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13. Hambardzumyan K, et al. Pre-treatment multi-biomarker disease activity score and radiographic progression in early RA: results from the SWEFOT trial. Ann Rheum Dis 2014. doi:10.1136/annrheumdis-2013-204986