Change in diagnosis alters clinical management and outcome.
“[…] despite the existence of well-established criteria for the diagnosis and microscopic staging of melanocytic lesions, there is still considerable disagreement among pathologists when faced with actual histologic specimens. Misdiagnosis and/or incorrect microscopic staging of melanocytic lesions can result in unnecessary psychological distress to the patient, undertreatment or overtreatment, inaccurate prognosis and improper follow-up, and family member surveillance.”
McGinnis KS, et al. Pathology review of cases presenting to a multidisciplinary pigmented lesion clinic. Archives of Dermatology 2002; 138:617-21.