Approximately 1 in 3 patients with platinum-resistant ovarian cancer will show FRα expression to qualify for therapy.1 Eligibility for ELAHERE is defined as tumor tissue that shows ≥75% tumor cells staining at 2+/3+ intensity.
Approximately 1 in 3 patients with platinum-resistant ovarian cancer (PROC) will show FRα expression to qualify for therapy.1 In the SORAYA study, patients who have received one to three lines of therapy, expressed FRA, and received mirvetuximab soravtansine-gynx demonstrated consistent clinically meaningful antitumor activity and favorable tolerability and safety.1 Eligibility for mirvetuximab soravtansine-gynx is defined as tumor tissue that shows ≥75% tumor cells staining at 2+/3+ intensity.
To support clinicians in determining FOLR1/FRα status in their ovarian cancer patients, Myriad is proud to offer FOLR1/FRα testing for patients with a diagnosis of epithelial ovarian cancer, fallopian tube, or primary peritoneal cancer.
FOLR1/FRα immunohistochemistry (IHC) testing can be ordered for:
To order FOLR1/FRα IHC Testing for your patients, download the Myriad Test Request Form (TRF).
National guidelines support the combined use of germline, genomic, and IHC testing to improve your patients’ outcomes, and Myriad offers a trusted one-stop solution for your testing needs. Our streamlined approach to delivering germline testing, tumor profiling, and companion diagnostic testing ensures you can quickly identify comprehensive treatment options for your patients.
Consider adding the following Myriad Genetics testing for your ovarian cancer patients:
Provider completes the test request form
Myriad Genetics receives the TRF and sends a tumor specimen collection kit to the pathology lab
Tumor sample† arrives at Myriad Genetics lab and FOLR1/FRα testing is performed
Results are sent to the ordering provider in the mail
Tumor block is returned to the pathology lab immediately after result reporting (slides will not be returned)
†FOLR1/FRα is run on FFPE sample or tissue with 50-100 tumor nuclei present on 2 slide sections 4 microns thick, placed on unstained, unbaked, positively charged slides.