• Genes Breast Ovarian Colorectal Uterine Skin Pancreatic Gastric Prostate Renal Lung Endocrine Other
    Hereditary Breast and Ovarian Cancer syndrome (HBOC)
    Lynch syndrome/Hereditary Non-Polyposis Colorectal Cancer (HNPCC)
    Hereditary Diffuse Gastric Cancer (HDGC)
    Familial Adenomatous Polyposis (FAP)/Attenuated Familial Adenomatous Polyposis (AFAP)
    MUTYH-associated Colorectal Cancer Risk
    MUTYH-associated Polyposis syndrome (MAP)
    Melanoma-Pancreatic Cancer Syndrome (MPCS)
    Melanoma Cancer Syndrome (MCS)
    Li-Fraumeni Syndrome (LFS)
    PTEN Hamartoma Tumor Syndrome (PHTS)
    Peutz-Jeghers Syndrome (PJS)
    Hereditary Diffuse Gastric Cancer (HDGC) Syndrome
    PALB2-associated Cancer Risk
    ATM-associated Cancer Risk
    CHEK2-associated Cancer Risk
    CHEK2-associated Cancer Risk (biallelic)
    RAD51C-associated Cancer Risk (Women only)
    RAD51D-associated Cancer Risk (Women only)
    BARD1-associated Cancer Risk (Women only)
    BRIP1-associated Cancer Risk (Women only)
    Juvenile Polyposis Syndrome (JPS)
    Juvenile Polyposis Syndrome (JPS) and Hereditary Hemorrhagic Telangiectasia (HHT)
    Von Hippel-Lindau Syndrome (VHL)
    Multiple Endocrine Neoplasia Type 2A (MEN2A), Familial Medullary Thyroid Cancer (FMTC), or Multiple Endocrine Neoplasia Type 2B (MEN2B)
    Multiple Endocrine Neoplasia Type 1 (MEN Type 1)
    BAP1-Tumor Predisposition Syndrome (BAP1-TPDS)
    Tuberous Sclerosis Complex (TSC)
    Hereditary Leiomyomatosis and Renal Cell Carcinoma syndrome (HLRCC)
    BIRT-HOGG-DUBE Syndrome (BHDS)
    TERT-associated Cancer Risk
    MITF-Associated Cancer Risk
    Hereditary Papillary Renal Cell Carcinoma (HPRCC)
    Hereditary Pheochromocytoma-Paraganglioma syndrome (Hereditary PPGL syndrome)
    Polymerase Proofreading-associated Polyposis (PPAP)
    Hereditary Mixed Polyposis Syndrome (HMPS)
    AXIN2-associated Cancer Risk
    Carrier Status for NTHL1-associated Cancer Risk
    NTHL1-associated Cancer Risk
    Carrier Status for MSH3-associated Cancer Risk
    MSH3-associated Cancer Risk
    HOXB13-associated Cancer Risk (Men only)
    EGFR-associated Cancer Risk

In addition to the genes listed above, Myriad Genetics MyRisk Hereditary Cancer Test includes RiskScore®, a precision medicine tool that predicts a woman’s five year and lifetime risk for developing breast cancer. RiskScore analyzes over 100 genetic markers combined with the Tyrer-Cuzick model to estimate a woman’s risk for developing breast cancer.

RiskScore is calculated for women under age 85 without a personal history of breast cancer, LCIS, hyperplasia, atypical hyperplasia, or a breast biopsy with unknown results. RiskScore is not calculated if the patient is known to carry a mutation in a breast cancer risk gene other that CHEK2, or if there are any known mutations in high-penetrance breast cancer risk genes in the patient’s family.

To learn more about RiskScore and the medical management guidelines provided for patients identified to have a remaining lifetime risk of breast cancer >20%, you may view the result insert by clicking the link below.

View RiskScore Insert

Genes selected for MyRisk satisfy these criteria:

  • Cancer Focus
    • Hereditable contribution
    • Association with overlapping syndromes
  • Penetrance
    • Cancer risk is at least 2-3 times the general population
  • Clinically Significant
    • Based on increased cancer risk from societal guidelines or determined by multiple studies
    • Change in management inferred based on risk level

Each gene tested with MyRisk links to one or more of 11 cancer sites:
Breast, Ovarian, Colorectal, Uterine, Skin, Pancreatic, Gastric, Prostate, Renal, Lung, and Endocrine.

MyRisk simplifies the test selection process by providing you the most comprehensive hereditary cancer panel test with clinically significant results. Be confident you are testing for the primary clinically significant genes associated with your patients’ risk.

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