Myriad Biopharma

Complex Decisions.
High Stakes.
Delivered Collaboratively.​

Biopharma success depends on getting critical diagnostic decisions right, from biomarker strategy to patient selection to global approval.

We support you as you navigate scientific and clinical complexity, from clinical development through regulatory approval and commercial launch.​

See how we help biopharma teams navigate diagnostic complexity

Three critical diagnostic decisions determine whether programs succeed:

1.

Your biomarker looks promising in preclinical data, but is the evidence strong enough to build a clinical program around it?

2.

Patient selection is where strategy meets reality. Are you identifying the patients most likely to demonstrate the benefit your therapy can deliver?

3.

Regulatory expectations vary across markets. Will your diagnostic strategy hold up across the FDA, PMDA, IVDR and the regulatory pathways you'll need for global launch?

A partner in making the right diagnostic decisions

You’re making high-stakes decisions under uncertainty, where scientific complexity, clinical realities, and regulatory expectations intersect.
We work alongside your team to define and evolve diagnostic strategies as your program progresses.
We combine clinically grounded judgment, adaptive ways of working, and rigorous regulatory execution to design diagnostic strategies that reduce complexities and strengthen drug development decision-making, towards optimizing patient outcomes.

From strategy to execution:
the platforms behind our impact

Our diagnostic strategies are supported by a comprehensive portfolio of genomic tests and platforms deployed across the oncology lifecycle, from early risk assessment to monitoring and recurrence.

Supporting diagnostic decisions across the oncology lifecycle

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Make biomarker strategies clinically actionable

Before a biomarker can support a clinical program, it must withstand scientific, technical, and real-world variability.

We help you:

  • Evaluate your biomarker across the right platforms to ensure robust and reproducible signals
  • Pressure-test its clinical relevance early with deep scientific and translational expertise
  • Ensure consistent results across global trial sites, reducing variability that can compromise outcomes

So you can move forward with confidence, knowing your biomarker is strong enough to support a clinical program.

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Identify the right patients for clinical success

If the right patients aren’t identified early, trials can fail to demonstrate therapeutic benefit.

We help you:

  • Align patient selection with biomarker strategy and trial design to maximize the likelihood of demonstrating efficacy
  • Access the right patients globally through integrated testing and a scalable lab network
  • Leverage validated diagnostics and real-world experience to reduce enrollment risk and variability

So you can generate clear, clinically meaningful outcomes — and reduce the risk of missing endpoints or costly trial redesigns.

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Ensure your diagnostic strategy holds up through approval and global launch

A diagnostic strategy that works in development may not withstand regulatory scrutiny or scale globally.

We help you:

  • Design companion diagnostics that meet regulatory expectations from the start, reducing downstream risk
  • Navigate complex approval pathways (FDA, PMDA, IVDR and beyond) with strategies built for global alignment
  • Prepare for real-world deployment through established partnerships and commercialization infrastructure

So your diagnostic strategy not only gets approved — but is also ready to scale with your therapy.

Proven experience supporting high-stakes diagnostic decisions

Scientific leadership

30+

years of genetic testing leadership through Myriad Genetics

1000+

scientific publications

Discovery

of BRCA1 and BRCA2 genes

Biopharma track record

70+

biopharma development projects

100+

clinical trials supported

20+

biopharma partners

Regulatory success

15+

FDA and PMDA approvals for companion diagnostics

2

commercially available CDx products

1st

Laboratory Developed Test approved as CDx by the FDA

Strategic Partnerships

Illumina logo

Sequencing platforms supporting comprehensive genomic profiling & IVD companion diagnostics

Qiagen logo

Development and global commercialization of IVD companion diagnostics

Sophia Genetics logo

Development & global commercialization of LBx and tissue-based companion diagnostics

Burning Rock Dx logo

Development & commercialization of CDx for China

Explore our diagnostic platforms and capabilities

Our capabilities span multiple platforms, modalities, and development pathways, enabling flexible and scalable diagnostic strategies tailored to each program.

Established diagnostic platforms

Proven tests supporting biomarker validation, patient selection, and clinical decision-making

  • BRACAnalysis® CDx – Germline testing for BRCA1/2 mutations
  • MyChoice® CDx – Tumor testing for BRCA1, BRCA2 and determination of Genomic Instability Score
  • MyRisk® – Germline testing for hereditary cancer gene panel
  • Precise MRD – Tumor-normal WGS-based ultrasensitive assay allows for flexibility and deeper analysis

Comprehensive genomic profiling & data generation

Flexible platforms to support discovery, validation, and translational insights

  • TSO 500 ± HRD – RUO, IUO and IVD versions of TSO 500 CGP product ± HRD kit add-on
  • RUO testing – Delivery of whole exome and whole genome data sets
  • MSK-ACCESS / MSK-IMPACT – RUO and CTA versions in partnership with SOPHiA GENETICS

Development, validation & regulatory enablement

End-to-end capabilities to support assay development and approval

  • De novo assay development and customization
  • CTA development & kit-based assay integration
  • Analytical & clinical validation services
  • Multi-platform support: NGS, qPCR, dPCR, IHC

Growing our companion diagnostic partnerships

QIAGEN logo
Pfizer logo
Illumina Logo
Burning Rock Dx Logo
Sophia Genetics Logo
Merck Logo
Astrazenecz Logo
GSK Logo
Personalis Logo