Image of Carmen, a Myriad Oncology patient, who has used a Precise® Tumor molecular profile test

Precise Tumor® Molecular Profile Test

Comprehensive tumor genomic profile testing for advanced solid tumors

The Precise Tumor Test simplifies patient care for clinicians by providing straightforward interpretations, prioritization of therapies, and the next steps specific to each patient’s tumor genomic results.

The Precise Tumor Test delivers clarity and actionable answers

The Precise Tumor Test is a next generation sequencing assay that analyzes more than 500 cancer-related genes, as well as key immuno-oncology biomarkers such as microsatellite instability (MSI) and tumor mutational burden (TMB), with broad coverage of guidelines.1

  • Quickly determine the next steps for your patients by identifying actionable genomic variants and biomarkers associated with FDA-approved therapies and clinical trials
  • Access all the information you need in a clear, concise report with evidence-based prioritization of biomarkers
  • Precise Tumor combines DNA and RNA sequencing to detect more fusions and splice variants compared to DNA-only tests2-5

Image of Carmen, a Myriad Oncology patient, engaging in daily activities and hobbies

The Precise Tumor Test includes DNA, RNA, and immuno-oncology biomarkers for more actionable findings

Diagram showing how the Precise® Tumor test includes DNA, RNA, and immune-oncology biomarkers for more actionable findings. Diagram showing how the Precise® Tumor test includes DNA, RNA, and immune-oncology biomarkers for more actionable findings.

The Precise Tumor Test combines DNA and RNA sequencing to detect more fusions and splice variants compared to DNA-only tests2-5

A comprehensive panel delivering actionable insights for multicancer care

The Precise Tumor Test identifies clinically relevant DNA and RNA variants to help guide personalized treatment decisions. By focusing on key guideline-recommended biomarkers and emerging pan-cancer targets, the Precise Tumor Test enables comprehensive and confident treatment planning.

Explore key cancer-specific biomarkers:

Key breast cancer biomarkers included in the Precise® Tumor molecular profile test
Key colon cancer biomarkers included in the Precise® Tumor molecular profile test
Key lung cancer biomarkers included in the Precise Precise® molecular profile test
Key ovarian cancer biomarkers included in the Precise® Tumor molecular profile test
Key pancreatic cancer biomarkers included in the Precise® Tumor molecular profile test
Key pan-cancer biomarkers included in the Precise Precise® molecular profile test
Key endometrial cancer biomarkers included in the Precise® Tumor molecular profile test
ey prostate cancer biomarkers included in the Precise® Tumor molecular profile test

How to order the Precise Tumor Test

Provider completes the test request form (in the EMR system, portal or via paper TRF)

Provider completes the test request form (in the EMR system, portal or via paper TRF)

Our laboratory processing staff will contact your pathology partner directly to obtain the tumor sample for Precise Tumor Testing

Our laboratory processing staff will contact your pathology partner directly to obtain the tumor sample for Precise Tumor Testing

Results will be reported in the provider portal as they become available

Results will be reported in the provider portal as they become available

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All your Myriad Oncology testing and results in your preferred EMR System

If you already count on the MyRisk Test, you’ll soon have even more reason to choose Myriad.

We’re bringing Precise Tumor Molecular Profile Test, MyChoice® CDx Myriad HRD Companion Diagnostic Test, and immunohistochemistry (IHC) testing for PD-L1 and FOLR1/FRa into your preferred EMR system workflow, so you can order germline and tumor genomic tests in one seamless process, from a single lab.​

Myriad Oncology empowers you to transform patient care

For a complete approach to cancer risk management and treatment planning, Precise Tumor can be combined with The MyRisk Test and appropriate tumor test to deliver powerful results informing patient care across the entire journey-from assessing hereditary cancer syndromes to guiding treatment decisions.

Precise Tumor® Molecular Profile Test MyRisk Hereditary Cancer Test

Combine germline and tumor genomic insights to identify hereditary cancer risks and actionable gene variants, enabling personalized treatment plans and targeted therapies. The MyRisk Test and the Precise Tumor Test focus on clinically relevant variations in the genome, where each test couples RNA analysis with DNA sequencing to provide more refined interpretation of results.

MyChoice Test MyRisk Hereditary Cancer Test

Integrate germline and tumor genomic profiling with HRD testing to identify more patients most likely to benefit from PARP inhibitors. The Precise Tumor Test and the MyChoice Test deliver a powerful combination of actionable tumor genomic information and homologous recombination status, optimizing treatment strategies for ovarian cancers.

Endopredict Breast Cancer prognostic Test MyRisk Hereditary Cancer Test

For your patients with early-stage breast cancer, pair germline testing with tumor genomic insights and breast cancer recurrence assessment to help guide personalized decisions on risk-reducing surgeries and adjuvant therapy strategies.

Myriad Oncology’s portfolio of products delivers:

  • Integrated genetic and tumor genomic insights to personalize care for each cancer patient
  • Confident risk and recurrence assessments to inform both preventive and therapeutic decisions
  • Streamlined reporting to prioritize actionable insights at every step of the cancer journey

What to expect with every Precise Tumor Test

Actionable

The Precise Tumor Test simplifies patient care for oncologists by providing straightforward interpretations, prioritization of therapies, and the next steps specific to each patient’s genomic results.

Accurate

The Precise Tumor Test combines DNA and RNA sequencing to detect more fusions and splice variants compared to DNA-only tests.2-5 Precise Tumor is validated to 98.91% analytical sensitivity and >99.99% analytical specificity.1

Affordable

Transparent pricing for genetic results with financial assistance and other affordability options.

Clinical resources

References:
  1. Conroy JM, Pabla S, Glenn ST, et al. A scalable high-throughput targeted next-generation sequencing assay for comprehensive genomic profiling of solid tumors. PLoS One. 2021;16(12):e0260089.
  2. Benayed R, Offin M, Mullaney K, et al. High yield of RNA sequencing for targetable kinase fusions in lung adenocarcinomas with no mitogenic driver alteration as detected by DNA sequencing and low tumor mutation burden. Clin Cancer Res. 2019;25(15):4712-4722.
  3. Wong W, Butaney M, Schneider J, et al. Methods for identifying patients with tropomyosin receptor kinase (TRK) fusions. Pathol Oncol Res. 2020;26(3):1385-1399.
  4. Yang Y, Qin G, Li Y, et al. A performance comparison of commonly used assays to detect RET fusions. Clin Cancer Res. 2020;26(24):6547-6556.
  5. Radonic T, Geurts-Giele WRR, Samsom KG, et al. RET FISH analysis is a sensitive but highly unspecific method for RET fusions in lung cancer. J Thorac Oncol. 2021;16(2):258-265.

©2025 Myriad Genetics, Inc., Myriad Genetics, Myriad Oncology, MyRisk, Precise Tumor, MyChoice, Prolaris, BRACAnalysis CDx, RiskScore, and their respective logos, are either trademarks or registered trademarks of Myriad Genetics, Inc and its subsidiaries in the United States and other jurisdictions. Eurobio Scientific has licensed the EndoPredict test to Myriad Genetics in select territories.