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Noninvasive prenatal screening provides important information.
Most women get reassuring results that their pregnancy is at low risk for chromosome abnormalities. However, if a screen turns up something unusual, a healthcare provider will discuss what it means and will offer a follow-up diagnostic procedure to confirm the results. This may be chorionic villus sampling (CVS) or amniocentesis.
The Prequel Prenatal Screen is a screening test, not a diagnostic test. This means it cannot give a definitive answer as to whether or not a pregnancy is affected by a chromosome condition. To confirm positive screening results, a follow-up diagnostic test will be needed and should be discussed with the patient’s provider.
The Prequel Prenatal Screen is a noninvasive prenatal screen that uses cell-free DNA (cfDNA) to determine if a pregnancy is at an increased risk for common chromosome abnormalities, such as Down syndrome.
cfDNA screening has been shown to be superior to methods that use maternal age, ultrasound, and serum screening. This results in a lower false-positive rate and false-negative rate.1
The Prequel Prenatal Screen can be ordered together with the Foresight® Carrier Screen and offered to all women, including those with high BMI, an ovum donor or a twin pregnancy.