MyRisk® Hereditary Cancer Test RiskScore®

A comprehensive approach to cancer risk assessment and care planning

If you have a personal or family history of cancer, genetic testing for cancer risk can help you understand your individual risk, allowing you and your provider to make informed healthcare decisions.

Know Your Risk. Plan for your Future.

What is genetic testing for hereditary cancer risk?

Hereditary cancer testing is a type of genetic test that can help you and your healthcare provider find out if you’re at higher risk for developing cancer due to certain types of genetic changes that may have been passed down through your family.

  • If you have a genetic change, your parents, children, and siblings have a 50% chance of having the same genetic change.
  • Other blood relatives on the same side of the family are at risk of carrying the same genetic change.
  • Testing is the primary way to identify gene changes, which could impact your medical management, including options that may reduce your risk of developing cancer.

MyRisk Hereditary Cancer Test - Gene wheel

Individuals with a concerning family history of cancer, including breast and ovarian, should consider genetic testing for cancer risk.

Confident decisions begin with the MyRisk Test

If you have a significant personal or family history of cancer, the MyRisk Test can help you understand your own risk of developing 11 different types of cancer. It can also provide important information for your family members if your test reveals a genetic change associated with hereditary cancer.

Your test results will include an individualized report with steps you and your healthcare provider can take to actively manage, and possibly lower, your cancer risk.

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A more complete picture of cancer risk with RiskScore

For many patients, the MyRisk Test results also include RiskScore, a personalized 5-year and remaining lifetime risk estimate for developing breast cancer. Available to people of all ancestries, this information can help you and your healthcare provider manage your risk now and into the future.

48 hereditary
cancer genes

Personal &
family history

(Tyrer-Cuzick V8)

Tyrer-Cuzick V8

Breast cancer
genetic risk markers

Ancestry
genetic markers

RiskScore: Twice as accurate as the Tyrer-Cuzick breast cancer risk assessment alone3

When it comes to understanding your risk for breast cancer, providers have traditionally relied on the Tyrer-Cuzick model, also known as the IBIS model. This tool looks at factors like your age, weight, breast density and family history to estimate your chances of developing breast cancer over time. It’s widely used and recommended by leading medical organizations.

RiskScore builds on this trusted model by adding genetic data from more than 90 markers linked to breast cancer risk. Patients benefit by having a clearer, more accurate picture of their personal breast cancer risk — about twice as accurate as the Tyrer-Cuzick risk assessment alone.3 This means you and your provider can make better decisions about screening, prevention and early detection, when treatment is most effective. Even if you don’t test positive for a hereditary cancer gene mutation, RiskScore can still uncover important insights that may change the way your care is managed.

“I believe if Dr. Frantz had never recommended the MyRisk genetic testing, the cancer wouldn’t have been found as early as it was. I don’t know if I’d be sitting here today.”

Get started with MyRisk

Work with your provider

Testing for hereditary cancer with your healthcare provider ensures a personalized and thorough assessment. Your doctor can integrate your test results with your medical history, providing tailored advice, and immediate follow-up actions. This approach offers clarity, emotional support, and a comprehensive plan for managing your health.

Virtual care

Busy schedule? No problem. Our virtual care solution allows you to work virtually with a healthcare professional to order, complete, and submit the MyRisk test from the comfort of your home.

You’ll have access to board-certified genetic counselors who can guide you through the process and the results of your test without ever stepping foot out your door.

Knowledge is power

Knowing if you are at higher risk for cancer allows you to make potentially life-saving medical decisions.

You and your healthcare provider can work together to create a personalized plan to possibly reduce your risk of developing cancer or increase the likelihood of finding cancer at an earlier and more treatable stage.

Your personalized prevention or treatment plan may include the following:

Additional
screening

Additional or modified screening such as an earlier age to begin mammography or the addition of breast MRIs may find cancer at an earlier and more treatable stage.

Risk-reducing
medications

There are medications that can lower your risk for certain cancers.

Risk-reducing
surgery

Certain surgeries can greatly lower your risk.

Treatment
options

If you’ve been diagnosed with cancer, your test results may help determine appropriate treatment options for you.

Explore hereditary cancer types

Certain genetic changes can put people at higher risk for these 11 types of hereditary cancer. Learn more about these cancer types and their associated genes below.

  • Breast cancer
  • Ovarian cancer
  • Prostate cancer
  • Pancreatic cancer
  • Uterine cancer
  • Colorectal cancer
  • Skin cancer
  • Gastric cancer
  • Renal cancer
  • Lung cancer
  • Endocrine cancer
  • Other

Genetic testing that’s affordable, results that are secure

Affordable

Most commercial and federally-funded insurance plans cover hereditary cancer testing4, and the majority of patients face no out-of-pocket costs for the MyRisk Test.5 For those that do, we provide clarity about any out-of-pocket cost, and we offer options to make testing accessible and affordable.

MyRisk Hereditary Cancer Risk - Affordable

Accurate

Myriad tests offer industry-leading accuracy so you can feel confident in the results. From hereditary cancer to precision medicine, our tests are designed to give patients and their healthcare providers the most accurate answers possible.

MyRisk Hereditary Cancer Test - Accurate

Secure

Myriad protects your personal information and takes steps to ensure patient data is secure. Myriad will not release genetic testing results to anyone other than you or the clinician who ordered your test – unless you provide permission.

Simple

Myriad makes genetic testing simple with clear, actionable results. We created easy-to-understand reports to ensure that both you and your clinician can use the information to guide care based on national medical guidelines.

MyRisk Hereditary Cancer Risk Simple

Related resources

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MyRisk Test gene table

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Documents & forms

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Latest studies & publications

References:
  1. https://myriad.com/gene-table

  2. NIH SEER data https://seer.cancer.gov/ accessed April 2022.

  3. Mabey B, Hughes E, Kucera M, et al. Validation of a clinical breast cancer risk assessment tool combining a polygenic score for all ancestries with traditional risk factors. Genet Med. 2024;26(7):101128.

  4. CDC. Retrieved from: https://www.cdc.gov/high-quality-care/hcp/resources/preventive-services-coverage.html
  5. Based on a review of 12 months of past claim data for major insurance carriers across the US, most patients face no out-of-pocket costs for their MyRisk test. Last updated 2024.