Approximately 55,000 new cases of pancreatic cancer are diagnosed in the U.S. each year, some of which are caused by a gene mutation that can be passed from generation to generation.1 Pancreatic cancer is associated with multiple hereditary cancer syndromes. Because of this, it is important to know your complete cancer family history and evaluate which hereditary cancer syndrome may be the cause. When pancreatic cancer is the predominant cancer in a family, the most common known hereditary causes are mutations in the PALB2, BRCA2 and p16 genes.
Knowing your potential risk for hereditary pancreatic cancer can help you and your healthcare professional make better, more informed decisions about your health, before the onset of cancer or before a second cancer has had a chance to develop. Genetic testing for hereditary pancreatic cancer with the Myriad MyRisk® Hereditary Cancer test should possibly be considered if:*
To help you assess whether you may be benefit from hereditary cancer genetic testing, you can take the Myriad Hereditary Cancer assessment. This assessment can help you get the information you need to discuss your risk of cancer with your healthcare professional and ask for further evaluation.
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If the Myriad MyRisk Hereditary Cancer test confirms the presence of a PALB2, BRCA2, p16 or other gene mutation, the following medical management options may help reduce cancer risk and may either prevent or delay the onset of pancreatic cancer as well as detect the cancer at an earlier, more treatable stage:†
*Assessment criteria are based on scientific literature and expert opinion
**Close blood relative refers to first- or second-degree relatives. First-degree relatives include parents, siblings, and children. Second-degree relatives include grandparents, aunts/uncles and nieces/nephews.
†Any discussion of medical management options is for general informational purposes only and does not constitute a recommendation. While genetic testing and medical society guidelines provide important and useful information, all medical management decisions should be made based on consultation between each patient and his or her healthcare professional.
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